Research published in Nature Communications |
The Ben-Yakar research group has developed a large-scale microfluidic chip for high-throughput screening of C. elegans disease models, published in Nature Communications (Mondal et al. 2016; DOI 10.1038/ncomms13023). The platform enables high-resolution phenotyping of ~4,000 C. elegans from 96 different populations in approximately 15 minutes.
Using this platform, approximately 1,000 FDA-approved drugs were screened using a polyglutamine-induced aggregation model of C. elegans to identify four confirmed hits.
New platform for roundworms could speed up drug deliveryNew device speeds up neurodegenerative disease researchNewormics, Cogitai and Opticlean pitch at UT Austin’s Startup Studio
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Prof. Adela Ben-Yakar
Phone: 512.475.9280
Email: ben-yakar@mail.utexas.edu
Ben-Yakar Group Offices: ETC 7.113
Phone: 512.471.7342
FemtoLab: ETC 7.106 | Phone: 512.471.7342
Mechanical Engineering Department C2200
University of Texas at Austin, Austin TX 78712
Shipping Address:
204 E. Dean Keeton Street Stop C2200
Austin, TX 78712-1591